Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats

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چکیده

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Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats

BACKGROUND Metabolic syndrome (coexisting visceral obesity, dyslipidemia, hyperglycemia, and hypertension) is a prominent risk factor for cardiovascular morbidity and mortality, however, its effect on cardiac gene expression pattern is unclear. Therefore, we examined the possible alterations in cardiac gene expression pattern in male Zucker Diabetic Fatty (ZDF) rats, a model of metabolic syndro...

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Myelodysplastic syndromes (MDSs) are a clonal bone marrow (BM) disease characterized by ineffective hematopoiesis, dysplastic maturation and progression to acute myeloid leukemia (AML). Methylation silencing of HRK has been found in several human malignancies. In this study, we explored the association of HRK methylation status with its expression, clinical parameters and MDS subtypes in MDS pa...

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The Pattern of Brain-Derived Neurotrophic Factor Gene Expression in the Hippocampus of Diabetic Rats

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ژورنال

عنوان ژورنال: Cardiovascular Diabetology

سال: 2013

ISSN: 1475-2840

DOI: 10.1186/1475-2840-12-16